Ready! Set! Go! (8 fl. oz) Kids Formula

Description

Ready! Set! Go! is a blend of fruits and plant extracts for children with occasional constipation. The ingredients in this blend have been used historically for the relief of occasional constipation and to soothe the stomach. The formula contains prunes, whose juice is often consumed as a home remedy for loosening bowels, and fiber-rich figs. In addition, the formula contains psyllium seed husks, one of the most widely used natural bulking fibers; both the psyllium seeds and husks are 100% organic. Ginger, fennel and coriander are added to help soothe the stomach. Ready! Set! Go! has a pleasant flavor for easy compliance.

Overview Occasional constipation is a common condition, caused in part by poor diet and lifestyle. The prevalence of refined sugars and carbohydrates and the low presence of fiber in the modern diet has been linked to the slowing of bowel transit time and the alteration of the colonic environment.1 Dietary fiber, which is mostly obtained from plant foods, consists of the indigestible portion of the plant while the sugars, starches and vitamins are broken down into nutrients and absorbed by our intestines. These cell walls of plants are not digested and become the bulk or roughage component of the stool, which help maintain bowel health and regularity. Psyllium in Ready! Set! Go! is comprised of soluble fiber (71% by weight), which has a high water-holding capacity, thus serving to increase stool frequency and weight. The additional blend of other fibers in the formula makes it effective for ongoing regularity, as well as overall gastrointestinal health.

Research† Several clinical trials have shown psyllium to be superior to other laxatives.2 A systematic review found psyllium husk to improve overall bowel regularity more effectively than lactulose.3 Psyllium has been found to be more effective than placebo at increasing stool output and was found to improve symptoms of occasional constipation including abdominal comfort, defecation effort, and sense of evacuation completeness. A randomized controlled trial found psyllium to have a significantly greater effect when supporting those with long term bowel irregularity and discomfort during the first and second month of treatment.4 The laxative effect and gut-stimulatory effect of psyllium has been purported to be mediated partially by muscarinic and 5-HT(4) receptor activation, which is thought to complement the laxative effect of psyllium’s fiber content.4 Psyllium’s gut-inhibitory activity may be mediated by the blockade of Ca(2+) channels and the activation of NO-cyclic guanosine monophosphate pathways.4 In addition, studies have also found that a 15 g dose of psyllium given 3 times per day before meals promoted healthy blood sugar and fat levels over a six-week period.5,6

Directions Children up to 6: 1-3 teaspoons daily as needed or as needed or as recommended by your health care professional.
Children 6-12: 1-2 tablespoons daily as needed or as needed or as recommended by your health care professional.
Adults: 2-3 tablespoons daily or as needed or as recommended by your health care professional.

Does Not Contain Gluten, corn, yeast, artificial colors and flavors.

Cautions If you are pregnant or nursing, consult your physician before taking this product.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References
1. Frizelle F. Constipation in adults. Clin Evod (online). 2007;0413(August 1).
2. Mehmood, Aziz. Pharmacological basis for the medicinal use of psyllium husk (isphagula) in constipation and diarrhea. Dig Dis Sci. 2011;56(5):1460-1471.
3. Kruis W, Forstmaier G, Scheurlen C, Stellaard F. Effect of diets low and high in refined sugars on gut transit, bile acid metabolism, and bacterial fermentation. Gut. 1991 Apr;32(4):367-71.
4. Bijkerk, Wit Nd, al MJe. Soluble or insoluble fiber in irritable bowel syndrome in primary care ? Randomized placebo controlled trial. BMJ. 2009;339:b3154.
5. Sierra M. Garcia JJ, Fernandez N, Diez MJ, Calle AP. Therapeutic effects of psyllium in type 2 diabetic patients. Eur J Clin Nutr. 2002 Sep;56(9):830-42.
6. Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP. Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia. Am J Clin Nutr. 1999 Oct;70(4):466-73.
7. Joseph B, Raj J. Pharmacognostic and phytochemical properties of Ficus carica Linn-an overview. Intl J Pharm Tech Research. 2011;3(1):8-12.
8. Kim S-Y, al HBe. Effect of Ficus carica on functional constipation. FASEB J. 2010;Abstract supplement iIB 348(April 24).