Lithium Synergy (120 capsules)

Lithium Synergy combines lithium orotate, known for its ability to help stabilize mood swings related to depression and other mood disorders, with vitamin B12 (methylcobalamin) and trimethylglycine to support healthy methylation pathways.



It is estimated that 26 percent of Americans suffer from mental disorders such as depression or bipolar disorder. Approximately 16 percent of Americans have been diagnosed with depression at some point in their lifetime. Clinically, it was Australian doctor, John Cade, who discovered lithium and its role in controlling bipolar disorder. Lithium orotate was introduced as a supplement by the German physician Dr. Hans Nieper, who used it to improve depression, headaches, migraine, epilepsy, and alcoholism. When salts of lithium are ingested, the lithium ions interact with several neurotransmitters and receptors in the central nervous system resulting in decreased norepinephrine release and increased serotonin synthesis.

Two studies published in 2009 concluded that even very low but sustained levels of lithium in drinking water may play a role in reducing suicide risk within the general population.1 In one study Japanese researchers evaluated lithium levels in the tap water of 18 municipalities. The researchers compared this data to the suicide standardized mortality ratio in each municipality from 2002 to 2006. The results of the study showed that as lithium levels increased, the suicide standardized mortality ratio averages decreased.

Other possible applications where lithium orotate may be of benefit:
• disruptive behavior disorders in children and adolescents7
• preventing episodic impulsive aggressiveness8
• protecting the brain from damage by alcohol9
• kleptomania
• preventing symptoms of Fragile X Syndrome (FXS)10 (FXS is a genetic flaw that causes certain forms of autism, learning disabilities, anxiety disorders, and mental retardation.)

Recommended Use: As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.

Serum lithium levels should be monitored by a qualified health care practitioner during use.

Cautions: This product should not be used to replace any antidepressant medication, including prescription forms of lithium, unless under the direction of a qualified health care practitioner. Lithium Synergy should not be used by individuals with significant renal or cardiovascular diseases, severe debilitation, dehydration or sodium depletion, or by individuals who are taking diuretics or ACE inhibitors. Consult your doctor before use if you are taking antihypertensive drugs, antiinflammatory drugs, analgesic drugs or insulin. Lithium should not be used by pregnant women and breast-feeding mothers. Serum lithium levels should be monitored by a qualified health care provider during use.


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